In a clinical trial of nasonex, 300 allergy patients were randomized

In a clinical trial of Nasonex, 300 allergy patients were randomized into two groups, with Group 1 receiving the Nasonex drug (200 mg) and Group 2 receiving a placebo. The experimenter used a 2:1 randomization plan so that more subjects would be assigned to the Nasonex group. One outcome of interest is the incidence rate of headache as a side-effect. Of the 200 patients randomized to the Nasonex group, 52 (or 26%) reported experiencing a headache; and of the 100 patients randomized to the placebo group, only 22 (22%) reported a headache.

A. The makers of Nasonex are concerned that their allergy medication might increase the incidence of headaches. So they would like to assess if the incidence rate of headaches is significantly higher for Nasonex users as compared to placebo (at the 5% level). So the null hypothesis is given by H0: p1 = p2. Select the appropriate alternative hypothesis.
i. Ha: p1 not equal to p2
ii. Ha: p1 > p2
iii. Ha: p1 < p2

B. It is important to understand what the various parameters in the hypotheses represent. Consider the following incorrect definition for the parameter p1. 
“p1 is the proportion of Nasonex allergy patients in the sample who experience a headache”. Provide the two words to complete this statement: This definition would be correct if you replace the word Sample with the word Population. 

C. The test statistic is computed assuming the null hypothesis is true, that is, p1 = p2 = p. Which of the following is the best estimate of that common proportion p?
i. 0.1867
ii. 0.22
iii. 0.2467
iv. 0.26 

D. It seems that the sample sizes of 200 and 100 should be sufficiently large enough to use a normal approximation to compute the p-value. Provide verification that the sample sizes are large enough.

E. Provide an estimate of the difference in the headache rates for the population of all Nasonex patients versus population of all placebo patients; that is, an estimate of p1 – p2.

i. 0.04
ii. 0.05
iii. 0.06
iv. 0.07

Which of the following is the corresponding test statistic for testing the hypotheses in part (a)?
i. 0.76
ii. 0.96
iii. 1.16
iv. 1.36

Find the corresponding p-value. Describe what the sketch would look like of this p-value.

H. At a 5% significance level, state your statistical decision (reject or fail to reject the null hypothesis) and then write a one sentence conclusion (in the context of the problem).


Calculate your paper price
Pages (550 words)
Approximate price: -

Why Choose Us

Quality Papers

We value our clients. For this reason, we ensure that each paper is written carefully as per the instructions provided by the client. Our editing team also checks all the papers to ensure that they have been completed as per the expectations.

Professional Academic Writers

Over the years, our Acme Homework has managed to secure the most qualified, reliable and experienced team of writers. The company has also ensured continued training and development of the team members to ensure that it keep up with the rising Academic Trends.

Affordable Prices

Our prices are fairly priced in such a way that ensures affordability. Additionally, you can get a free price quotation by clicking on the "Place Order" button.

On-Time delivery

We pay strict attention on deadlines. For this reason, we ensure that all papers are submitted earlier, even before the deadline indicated by the customer. For this reason, the client can go through the work and review everything.

100% Originality

At Essay USA, all papers are plagiarism-free as they are written from scratch. We have taken strict measures to ensure that there is no similarity on all papers and that citations are included as per the standards set.

Customer Support 24/7

Our support team is readily available to provide any guidance/help on our platform at any time of the day/night. Feel free to contact us via the Chat window or support email:

Try it now!

Calculate the price of your order

We'll send you the first draft for approval by at
Total price:

How it works?

Follow these simple steps to get your paper done

Place your order

Fill in the order form and provide all details of your assignment.

Proceed with the payment

Choose the payment system that suits you most.

Receive the final file

Once your paper is ready, we will email it to you.

Our Services

Essay USA has stood as the world’s leading custom essay writing services providers. Once you enter all the details in the order form under the place order button, the rest is up to us.


Essay Writing Services

At Essay USA, we prioritize on all aspects that bring about a good grade such as impeccable grammar, proper structure, zero-plagiarism and conformance to guidelines. Our experienced team of writers will help you completed your essays and other assignments.


Admission and Business Papers

Be assured that you’ll definitely get accepted to the Master’s level program at any university once you enter all the details in the order form. We won’t leave you here; we will also help you secure a good position in your aspired workplace by creating an outstanding resume or portfolio once you place an order.


Editing and Proofreading

Our skilled editing and writing team will help you restructure you paper, paraphrase, correct grammar and replace plagiarized sections on your paper just on time. The service is geared toward eliminating any mistakes and rather enhancing better quality.


Technical papers

We have writers in almost all fields including the most technical fields. You don’t have to worry about the complexity of your paper. Simply enter as much details as possible in the place order section.